Kidney Educational Enrichment Program

The Kidney Educational Enrichment Program (KEEP) program will focus on a broad range of opportunities to excite and involve students and residents as well as new investigators in kidney disease research and will, at the same time, promote new interactions and opportunities between established investigators. KEEP will particularly focus on teaching and training in relation to Applied Systems Biology and promoting translational interactions between basic and clinical scientists. 

Program Committee 

This committee will oversee all aspects of the KEEP program. The main focus will be to evaluate efficacy of components of the KEEP program, especially those where Center resources are being used. 

  • Chip Brosius
  • Crystal Gadegbeku
  • Ben Margolis
  • David Kershaw
  • Sub Pennathur
  • Roger Wiggins

Seminars: 

NEW LOCATION! 2817 Med Sci II or virtually, by zoom

Join Zoom Meeting: https://umich.zoom.us/j/92714906102?from=addon

Meeting ID: 927 1490 6102
Passcode: 435458

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2016 - 2024

  • March 19, 2024
  • Jeffrey A. Beamish, MD, PhD, " A new look at an old topic: Proximal tubule primary culture as models for kidney disease"
  • March 12, 2024
  • Abhijit S. Naik, MBBS, "Extending kidney allograft longevity by modulating perioperative IGF-1 signaling"
  • March 5, 2024
  • Changyang Linghu, Ph.D., "Tools for multiplexed and scalable observations of cellular physiology"
  • February 27, 2024
  • Ken Inoki, MD, PhD, "Nutrient-sensing machinery for mTORC1 activation on the lysosome"
  • February 20, 2024
  • Jun Hee Lee, MS, PhD "Seq-Scope: Exploring Tissue Spatial Transcriptome With Microscopic Resolution"
  • February 6, 2024
  • Richard T. "Tyler" Miller, M.D, Internal Medicine Vice Chair, Va North Texas Health Care System, University of Texas Southwestern Medical School, "Early Pathways in Collagen IV Nephropathies"
  • January 30, 2024
  • Jennifer Schaub, MD "Potential impact of SGLT2 inhibitors on acid-base handling"
  • January 23, 2024
  • Judy Baek, MD/PhD Candidate "Role of Sirtuin 5 and malonylation in diabetic kidney disease"
  • January 16, 2024
  • Nicholas Ferrell, PhD "Biophysical regulation of kidney function in health and disease"
  • January 9, 2024: No Seminar
  • December 12, 2023
  • Guoming Gao, PhD candidate "Biomolecular condensates in kidney physiology and disease"
  • December 5, 2023
  • Matthias Tilmann Florian Wolf, MD "Identifying new therapies for Uromodulin associated kidney disease – from Klotho to High Throughput Assay Screening"
  • Madhav Menon, MD "Distinct domains in Shroom3 mediate proteinuria and fibrosis in native and allograft CKD"
  • November 21, 2023
  • Sriram Chandrasekaran, PhD "Systems Biology Tools for Drug Discovery & Metabolic Modeling"
  • October 24, 2023
  • Guest Speaker: Jan Stegemann, PhD, Modular Strategies for Regenerating Vascularized Tissues
  • October 17, 2023
  • Anna V Mathew, MBBS, Tryptophan catabolite quinolinic acid and vascular inflammation in CKD-associated atherosclerosis

  • October 3, 2023
  • Farsad Afshinnia, M.D. M.S. "Role of Acetyl Co-A carboxylase in type 2 diabetic kidney disease."

  • September 26, 2023

  • Jeffrey Beamish, MD, PhD “Proposal discussion: The role of Pax8 in fatty acid metabolism and protection from ischemic AKI"

  • September 19, 2023

  • Madhav Menon, MD "Making sense of non-HLA variants in Kidney transplantation: Bedside - to - Bench approaches"
  • June 20, 2023
  • Abhijit Naik, MD “Perioperative IGF-1 Signaling and Kidney Allograft Failure”, Associate Professor, Division of Nephrology, University of Michigan
  • May 30, 2023
  • Victor G. Puelles, MD will present “"Crossing biological scales in the kidney: from whole organs to subcellular structures. "
  • May 9, 2023
  • Jennifer Schaub, MD will present “Potential regulation of cell type enrichment of HIF-1A target genes in DKD.”
  • May 2, 2023
  • Samira Musah, Ph.D. will present “"Uncovering novel biomarkers of kidney disease. "
  • April 25, 2023
  • Farsad Afshinnia, M.D. M.S. will present: " Signature of Voclosporin-induced metabolic alterations in lupus nephritis: Implications in remission.”
  • April 18, 2023
  • Michal A. Olszewski, D.V.M., Ph.D. will present: " The Elusive Role of Nitric Oxide Synthase in Anti-Cryptococcal Host Defenses.”
  • April 11, 2023
  • Shayna Bradford, Ph.D. will present: " Role of TNIK in failed-repair proximal tubule cells.”
  • March 28, 2023
  • Bethany Moore, PhD will present “How fibrosis impacts innate immunity in the lung.”
  • March 14, 2023
  • Dr. Jeffrey Beamish will present: "Proximal tubule Pax gene loss protects against ischemic kidney injury”
  • March 7, 2023
  • Alla Karnovsky, Ph.D. presents: “Bioinformatics tools for network-based analysis and visualization of metabolomics data.”
  • February 28, 2023
  • Cristina Cebrián, Ph.D presents: “Becoming Distal: A Tale of Nephron Segmentation and Differentiation.”
  • January 31, 2023
  • Sandra Merscher, Ph.D. presents “Sphingolipids in Podocyte Injury and Glomerular Disease.”
  • January 24, 2023
  • H. David Humes, MD presents “Cell Directed Immunomodulation: A Platform Technology to Treat Acute Organ Failure. A Winding Road from Bench to Bedside.”
  • January 17, 2023
  • Dr. Richard Miller will present: "Drugs That Slow Aging in Mice and The Search For Shared Anti-Aging Mechanisms”
  • January 11, 2023
  • Dr. Jeffrey Beamish will present: " Defining a role for transcription factor EB (TFEB) in Polycystic Kidney Disease (PKD)"
  • December 13, 2022
  • Dr. Elizabeth Speliotes will present: "Advances in the Treatment of Obesity and NAFLD Guided by Human Genetics"
  • November 29, 2022
  • Dr. Jonathan Shillingford will present: " Defining a role for transcription factor EB (TFEB) in Polycystic Kidney Disease (PKD)"
  • November 8, 2022
  • Dr. Michael Boehnke will present: "Identifying genes for type 2 diabetes and related traits"
  • October 25, 2022
  • Dr. Anna Mathew will present: " Tryptophan catabolites and vascular inflammation in CKD associated atherosclerosis"
  • October 4, 2022
  • Dr. Wenjun Ju will present: "Towards Precision Medicine in Chronic kidney Disease: A Journey From "Correlation" to "Understanding the Correlation" At Molecular Level"
  • September 27, 2002
  • Dr. Rasheed A. Gbadegesin will present: " Defining the genetic architecture of podocytopathies: Then and Now"
  • September 20, 2022
  • Dr. Sriram Chandrasekaran will present: "Systems biology tools for drug discovery and studying metabolism"
  • June 21, 2022
  • Dr. John Varga will present: “Scleroderma insights: emerging therapeutic targets"
  • June 14, 2022
  • Dr. Abhijit Naik, MD will present: “The molecular landscape of BK polyomavirus infection in human kidney allograft recipients"
  • June 7, 2022
  • Dr. Jeffrey Beamish will present: “The role of Pax proteins in failed repair after ischemic acute kidney injury"
  • May 31, 2022
  • Dr. Jason Watts will present: “RNA structure regulates RNA polymerase pausing in renal proximal tubule cell"
  • May 17, 2022
  • Dr. Jennifer Schaub will present: "Impact of SGLT2 Inhibitors on HIF Signaling in Patients with DKD"
  • May 10, 2022
  • Dr. Jennifer Harder will present: " Modeling Kidney Disease using Human PSC-Organoids: Realizing the Promise "
  • May 3, 2022
  • Dr. Anuska Andjelkovic-Zochowska will present: "Blood brain barrier: brain "gatekeeper" in health and disease"
  • April 19, 2022
  • Dr. Jeffrey Hodgin will present: "NEPTUNE Pathology Studies Update"
  • March 29, 2022
  • Dr. Stephen Parker will present: "Single-nucleus multi-omics to dissect the context specificity of metabolic trait GWAS signals”
  • March 22, 2022
  • Dr. Linda Samuelson will present: " Notch Regulation of Intestinal Stem Cells”
  • March 15, 2022
  • Dr. Sethuramasundaram Pitchiaya will present: "Dynamic biomolecular assemblies modulate cellular stress responses”
  • March 8, 2022
  • Dr. Diane Fingar will present: "Crosstalk between mTOR and other regulatory systems”
  • March 1, 2022
  • Dr. Kanakadurga Singer will present: " Sex differences in obesity induced inflammation”
  • February 22, 2022
  • Dr. William (Bill) Rainey will present: "Historic, Genetic and Cellular Origins of Primary Aldosteronism”
  • February 8, 2022
  • Dr. Liangyou Rui will present: "Inflamed hepatocytes and bile duct epithelial cells in liver disease Progression”
  • February 1, 2022
  • Dr. Markus Bitzer will present: "Insights from Nephrectomies - PRECISE cohort"
  • January 18, 2022
  • Dr. Matthias Truttmann will present: " Protein AMPylation: a novel post-translational modification regulating proteostasis"
  • January 11, 2022
  • Dr. Rachel Zemans will present: "Physiologic and Fibrotic Lung Repair after Injury"
  • December 14, 2021
  • Dr. Lois Weisman will present: "New roles for the lipid kinases, Vps34 and PIKfyve via their generation of a phosphoinositide cascade"
  • November 30, 2021: SPECIAL CPROBE RETREAT
  • Dr. Farsad Afshinnia  will present: " Lipidomics of Systemic Complication in Type 2 Diabetes: Similarities and Differences Across Various End Organs "
  • https://umich.zoom.us/j/99707711167 
  • Meeting ID: 997 0771 1167           
  • Passcode: 201251 
  • November 16, 2021
  • Dr. H. David Humes will present: "Extracorporeal Immunomodulation: A Platform Technology to Treat COVID-19, Cytokine Storm, Acute Kidney Injury and Chronic Heart Failure"
  • November 9, 2021
  • Dr. Jun Wu will present: "A novel metabolic circuitry through acetylcholine and nAChR"
  • October 26, 2021
  • Dr. Christiane Wobus will present: "Pivoting virology research during a pandemic."
  • October 19, 2021: No session
  • October 12, 2021
  • Dr. Manoj Puthenveedu will present: "The importance of location in GPCR signaling"
  • October 5, 2021
  • Dr. Abhijit Naik will present: "Glomerular endothelial cell-podocyte stresses and crosstalk instructurally normal kidney transplants"
  • September 28, 2021
  • Dr. Karandeep Singh will present: "Bringing Machine Learning Models to the Bedside"
  • September 21, 2021
  • Dr. Anna Mathew will present: " Tryptophan immune metabolism and Cardiovascular Risk in Chronic Kidney Disease "
  • September 14, 2021
  • Dr. Yatrik Shah will present: "Oxygen Sensing Pathways in iron related disorders"
  • June 29, 2021
  • Dr. VIhba Lama, Pulmonary Critical Care, Vice Chair for Basic and Translational Research, will present: "Stem cells, fibrosis, and transplantation - A translational approach to investigating chronic graft failure"
  • June 22, 2021
  • Dr. Jennifer Schaub will present: "Expression of Hypoxia Related Genes in Diabetic Kidney Disease"
  • June 15, 2021
  • Dr. Jason Watts will present: "Nucleic acid sequence and structure regulates renal gene transcription"
  • May 25, 2021
  • Dr. Greg Dressler will present: " Targeting developmental pathways in kidney disease"
  • May 18, 2021
  • Dr. Wenjun Ju will present: "Toward Precision Medicine in Chronic Kidney Disease: Tissue-Driven Non-Invasive Mechanistic Biomarker Identification for Patient Stratification"
  • May 11, 2021
  • Dr. C Alberto Figueroa will present: "Image-based modeling of hemodynamics: Applications to Hypertension Research"
  • May 4, 2021
  • Dr. Jennifer Harder will present: "Update: Modeling human kidney disease with human PSC-kidney organoids"
  • April 26, 2021
  • Dr. Farhad R. Danesh will present: "Mitochondrial Regulation of Diabetic Nephropathy: Moving Beyond the Paradigm"
  • April 20, 2021
  • Dr. Jeffrey Beamish will present: "Molecular and Genetic Mechanisms of Kidney Regeneration"
  • April 13, 2021
  • There will be no conference today.
  • April 6, 2021
  • Dr. Janos Peti-Peterdi will present: "Physiological activation of the nephron central command drives tissue remodeling and repair"
  • March 23, 2021
  • Dr. Ryan Baldridge will present: "Exploring substrate selection by the ER associated degradation system"
  • March 16, 2021
  • Dr. Rujun Gong will present: "Therapeutic targeting of GSK3b in kidney disease."
  • March 9, 20201
  • Dr. Shuta Ishibe will present: "Novel Insights into the Treatment of Proteinuric Kidney Disease"
  • March 2, 2021
  • Dr. Michael Imperiale will present: " Studying BK Polyomavirus Persistence and Replication in a Cell Culture Model"
  • February 23, 2021
  • Dr. Pablo Ortiz will present: "Studying renal ion transport to find new salt sensitive hypertension genes: focus on NKCC"
  • February 16, 2021
  • Dr. Ann Miller will present: "Maintenance and remodeling of epithelial cell-cell junctions during cell shape changes"
  • February 9, 20221
  • Dr. Christian Faul will present: "Pathologic actions of FGF23 in chronic kidney disease"
  • January 26, 2021
  • Dr. Carey Lumeng will present: "Adipose Tissue Leukocytes in Obesity"
  • January 19, 2021
  • Dr. Ursula Jakob will present: " Early Life Oxidative Stress - A Modifier of Aging and Age-Associated Diseases"
  • December 15, 2020
  • Dr. James Shayman will present: "Substrate Reduction Therapy for Lysosomal Storage Disorders: Past, Present, and Future"
  • December 1, 2020
  • Dr. Roger Wiggins will present: " Connecting hyperfiltration to podocyte depletion via IGF-1. A unifying concept for kidney disease progression"
  • November 17, 2020
  • Dr. Ken Inoki will present: "New crosstalk between amino acid- and growth factor-induced mTORC1 activation on the lysosome"
  • November 10, 2020
  • Dr. Mats Ljungman will present: "A universal precision targeting approach for cancer using CRISPR"
  • October 27, 2020
  • Dr. Farsad Afshinnia will present: "Lipidomics of Diabetic Kidney Disease Progression: Similarities and Differences in Type 1 and 2 Diabetes"
  • October 13, 2020
  • Dr. Jun Li will present: "A new golden age of developmental biology"
  • October 6, 2020
  • Dr. Goutham Narla will present: "From mutations to small molecules: lessons learned from Protein Phosphatase 2A"
  • September 27, 2020
  • Dr. Nils Walter will present: "Single Molecules Come Into Focus: From RNA-Driven Regulation to Hyperosmotic Phase Separation to Digital Counting of Disease Biomarkers"
  • September 22, 2020
  • Dr. Douglas Atchison will present: “Angiotensin II Causes Sudden Death from Aortic Dissection in PLCE1-Deficiency”
  • July 28, 2020
  • Dr. Decker will present: “Characterization of Endothelial Cell Dysfunction in Fabry Disease by Measurement of the Ribosome Bound Transcriptome”
  • July 21, 2020
  • Dr. Jennifer Schaub will present "Hypoxia Signatures in Kidney Disease"
  • June 23, 2020
  • Dr. Byrd will present: "Extracellular vesicles as an emerging tool in the clinical investigation of hypertension.”
  • June 16, 2020
  • Dr. Watts will present: "RNA polymerase pausing in mitochondria and osmoregulation"
  • March 10, 2020
  • Dr. Welch will present: "Quantitative Definition of Cell Identity by Single-Cell Multi-Omic Integration"
  • March 3, 2020
  • Dr. Auchus will present: "Some alternative facts about androgen biosynthesis”
  • February 11, 2020 - CANCELED, TO BE RESCHEDULED
  • Dr. Byrd will present: "Extracellular vesicles as an emerging tool in the clinical investigation of hypertension."
  • February 4, 2020
  • Dr. Dressler will present: "Pax Genes and Epigenetic Pathways in Kidney Development and Disease”
  • January 28, 2020
  • Dr. David Ginsburg will present: "FV/FVIII and Cargo Receptors in the ER: From Bedside to Bench"
  • January 21, 2020
  • Dr. Knight will present: "The end of NET neutrality: are we ready to target neutrophils in antiphospholipid syndrome?"
  • January 14, 2020
  • Dr. Cleuren will present: "In vivo transcriptional profiling of endothelial cells in health and disease"
  • January 7, 2020
  • Dr. Mariani will present: "Outcome Prediction in Glomerular Disease"
  • December 17, 2019
  • Dr. Lombard will present: "SIRT5: SIRTainly a Central Player in the Heart and in Cancer"  
  • December 10, 2019
  • Dr. Carter-Su will present: " CRISPR/Cas9 gene editing reveals the importance of the PH domain and opposing actions of splice variants of the adapter protein SH2B1 in regulating energy balance and glucose metabolism
  • December 3, 2019
  • Dr. Bitzer will present: " Post-transcriptional Regulation of Gene Expression by microRNAs in the Kidney "  
  • November 26, 2019
  • No presentation due to the Thanksgiving holiday
  • November 19, 2019
  • Dr. Bielas will present: "ASXL3 at the Nexus of Chromatin and Autism Spectrum Disorders" 
  • November 12, 2019
  • Dr. Duan will present: " IGF Signaling and its Emerging role in Adaptive Epithelial Growth and Calcium Uptake
  • October 29, 2019
  • Dr. Lin will present: "Mapping the Landscape of Intercellular Signaling in Health and Metabolic Disease"  
  • October 22, 2019
  • Dr. Chun will present: " Adipocytes and Fibrosis Beyond Obesity"  
  • October 15, 2019
  • Dr. Sally Camper will present: “Mouse phenotypes are directly correlated to gene regulation: revealing MORE about promoters
  • October 8, 2019
  • Dr. Thomas Werner will present  “Mouse phenotypes are directly correlated to gene regulation: revealing MORE about promoters
  • October 1, 2019
  • Dr. Shreeam Akilesh will present  “Structure and Function of the Kidney Genome” 
  • September 24, 2019
  • Dr. Jonathan Shillingford will present “Understanding the role of glucosylceramide synthase inhibitors in Polycystic Kidney Disease (PKD)” 
  • September 17, 2019
  • Dr. Sean Eddy will present "JAK-STAT activation in glomerular disease: Beyond diabetic nephropathy"
  • September 10, 2019
  • Dr. Anna Mathew will present "Tryptophan Metabolism & Cardiovascular Risk in Chronic Kidney Disease
  • July 7, 2019
  • Dr. Salim Hayek will present “SuPAR in Kidney Disease: What Controversy?” 
  • June 18, 2019
  • Dr. Ilka Decker will present "Characterization of the endothelial cell dysfunction in Fabry Disease by direct measurement of the ribosome associated transcriptome" 
  • June 11, 2019
  • Dr. Doug Atchison will present “Angiotensin II Induces Focal Glomerulosclerosis and Sudden Death from Aortic Dissection in PLCE1 Deficiency” 
  • May 21, 2019
  • Dr. Abhijit Naik will present “Long term kidney allograft survival and donor kidney disease progression risk” 
  • May 14, 2019 - CANCELLED
  • May 7, 2019
  • Dr. Jeffrey Horowitz will present "Exercise effects on fatty acid metabolism in obesity: Impact on insulin resistance” 
  • April 30, 2019
  • Dr. Puneet Garg will present “Nephrin trafficking at the Slit diaphragm” 
  • April 23, 2019
  • Dr. Jeff Beamish will present “Modeling renal epithelial-microvascular interactions in vitro”
  • April 16, 2019
  • Dr. Jason Watts will present “RNA Polymerase Pausing and Its Effects on Human Gene Expression” 
  • April 2, 2019
  • No conference this week
  • March 26, 2019
  • Dr. Scott Soleimanpour will present “Mitophagy serves as a protective response to cellular inflammation in diabetes” 
  • March 19, 2019
  • Dr. Sami Barmada will present “RNA metabolism and TDP43-mediated toxicity in amyotrophic lateral sclerosis (ALS)" 
  • March 12, 2019
  • Dr. Jennifer Harder will present “Modeling Kidney Disease Using hPSC-derived Kidney Organoids” 
  • March 5, 2019
  • Dr. Pavan Reddy will present “Target Tissue Metabolism in T Cell Immunopathology"
  • February 26, 2019
  • Dr. Phyllis Hanson will present “How cells maintain membrane integrity – ESCRT function in endolysosomal homeostasis” 
  • February 19, 2019
  • Dr. Gabriel Fuentes will present  "Minimal change disease: an endothelial-podocyte disorder?" 
  • February 12, 2019
  • Dr. Jennifer Harder will present “Modeling Kidney Disease Using hPSC-derived Kidney Organoids” 
  • February 5, 2019
  • Dr. Roger Wiggins will present “Pathogenesis in Type 2 Diabetes-Associated Glomerular Nephropathy” 
  • January 22, 2019
  • Dr. Costas Lyssiotis will present “Metabolic Networks in the Tumor Microenvironment"
  • January 15, 2019
  • Dr. Indika Rajapakse will present “Reprogramming the Human Genome” 
  • January 8, 2019
  • Dr. Guojun Shi will present "The role of ER-associated protein degradation (ERAD) in health and disease"
  • December 18, 2018
  • Dr. Kelli Sas will present “Metabolic Reprogramming in Diabetic Microvascular Complications"
  • December 11, 2018
  • Dr. Lana Garmire will present "Multi-omics integration from population to single cell resolution"
  • December 4, 2018
  • Dr. Randy Seeley will present “Bariatric surgery:  It’s not what you think it is. Molecular underpinnings of the effects on obesity and diabetes” 
  • November 20, 2018
  • Dr. Andrew Tsai will present “Reorganizing cellular membrane trafficking to build a viral replication organelle: Lessons from hepatitis C and dengue virus” 
  • November 13, 2018
  • Dr. Steven Abcouwer will present "Resolution of Inflammation & Vascular Restoration in Diabetic Retinopathy"
  • November 6, 2018
  • Dr. Vania Hinkovska-Galcheva will present "New Insights into Structural & Functional Analysis of Lysosomal Phospholipase A2"
  • October 16, 2018
  • Dr Farsad Afshinnia will present "Lipidomics & CKD: From Markers to mechanisms" 
  • October 2, 2018
  • Dr. Greg Dressler will present "Pax genes and epigenetic regulation in kidney development and disease
  • September 25, 2018
  • Dr. James Morrissey will present “Polyphosphate: An Ancient Molecule with New Roles in Hemostasis, Thrombosis & Inflammation” 
  • September 11, 2018 NEW LOCATION! M5330 Med Sci I
  • Dr. Deepak Nagrath will present "Targeting Tumor & Microenvironment Using Metabolic Systems Biology"
  • June 19, 2018
  • Dr. Ilka Decker will present "The Endothelial Cell Transcriptome in Fabry Disease" and Dr. Doug Atchison will present "The Role of Phospholipase Ce1 in the Development of Proteinuria"
  • June 12, 2018
  • Dr. Jason Watts will present "Cis- and Trans-acting Determinants of RNA Polymerase Pausing in Human Cells"
  • June 5, 2018
  • Dr. Matt Sampson will present "A GWAS of Pediatric SSNS & Kidney Compartment Specific eQTL Maps"
  • May 22, 2018
  • Dr. Lois Weisman will present "From yeast to humans: Insights into phosphoinositide lipid signaling"
  • May 15, 2018
  • Dr. Jeffrey Beamish will present "Renal Epithelial Differentiation in Engineered Microvascular Niches"
  • May 8, 2018
  • Faculty candidate Dr. Markus Rinschen will present “Muti-Layered Proteomic Analysis of Podocyte Injury” 
  • May 1, 2018
  • Dr. Jacob Kitzman will present "Massively Parallel Approaches to Tackle Variants of Uncertain Significance"
  • April 24, 2018
  • Dr. Richard Mortensen: "“TCA cycle derivatives controlling ischemia/reperfusion and inflammation: Focus on itaconate” 
  • April 17, 2018
  • Dr. Puneet Garg: "Nephrin: Can I have some more?"
  • April 10, 2018
  • Dr. Ryan Mills - "Excavating the Deep Genome: Deciphering Structural Variation in Complex & Repetitive Regions"
  • April 3, 2018
  • Dr. Shigeki Iwase - "Impact of the Complex Brain Transcriptome on Chromatin and Synapses"
  • March 27, 2018
  • Dr. Joel Weinberg - "Searching for the Holy Grail - The Membrane Target for Glycine Cytoprotection"
  • March 20, 2018
  • Dr. Evan Farkash - "Late Renal Allograft Outcomes: ABMR, NK Cells, and Viral Oncogenesis"
  • March 13, 2018
  • Dr. Jorge Iniguez-Lluhi - "Nuclear Receptor Regulation Through SUO Modification: Impact on Human Disease"
  • March 7, 2018
  • Dr. Anna Mathew 'Cardiovascular Disease Risk & Dysfunctional High Density Lipoprotein"
  • February 26, 2018
  • No Basic Science Seminar
  • February 13, 2018
    Jun Li, PhD - "Single-cell genomics: Hitchhiking the Inner Galaxies"
  • February 6, 2018
    Michael Boehnke, PhD - "Identifying Genes for Type 2 Diabetes & Related Traits Using Genetic Association Studies"
  • January 30, 2018
    James Shayman, MD - "Son of Eliglustat"
  • January 23, 2018
    Maggie Chen, MD, PhD - "Endoplasmic Reticulum Stress & Genetic Mutations in Precision Nephrology"
  • January 16, 2018
    Roger Wiggins, MB, BChir - "Modeling Podocyte Hypertrophic Stress and its Consequences"
  • December 19, 2017
    Peter Arvan, MD, PhD - "Physiology & Disease in the Thyroid Epithelium"
  • December 12, 2017
    Anthony Antonellis, MD - Genetic and genomic approaches for studying peripheral nerve development & related human diseases"
  • November 28, 2017
    Jonathan M. Shillingford, PhD - "Interrogating Signaling Pathways in Polycystic Kidney Disease (PKD)"
  • November 21, 2017
    Dan Beard, PhD - "Multi-scale modeling and simulation in physiology: Examples from cardiac mechanics, metabolism, and whole-body cardiovascular dynamics"
  • November 14, 2017
    Charles Burant, MD - "High oxidative capacity, mechanisms underlying a long, healthy life!"
  • October 24, 2017
    Jennifer Schaub, MD - "Because It's There: Untangling Human AKI"
  • October 17, 2017
    Matthew Delano, MD - "Acute Kidney Injury is Complement Dependent in Diet Induced Obesity Following Trauma and Sepsis"
  • October 10, 2017
    Vivian Cheung, MD - "Why nucleic acid structure matters: Lessons from a motor neuron disorder"
  • October 3, 2017
    Daniel Goldstein, MD - "Novel Pathways of Aging + Inflammation"
  • September 26, 2017
    Michelle Kahlenberg, MD, PhD - "Lupus: Is there a skin/kidney connection?"
  • September 19, 2017
    Jun He Lee, PhD - "Systematic Characterization of Stress Granule Transcriptome"
  • June 27, 2017
    Eugene Rhee, MD - "Lipidomics: Biomarkers to Biology?"
  • June 20, 2017
    Jeff Hodgin, MD, PhD - "Caspase-1 and the Inflammasome in Glomerular Injury"
  • June 13,2017
    Toralf Melsom, PhD - "Hyperfiltration, Albuminuria & Rapid GFR decline in the General Non-Diabetic Population"
  • June 6, 2017
    Weibin Zhou, PhD - "What Can We Learn From Zebrafish Podocytes?"
  • May 30,2017
    Puneet Garg, MD - "Does Nephrin Have a Role in a Mature Slit Diaphragm?"
  • May 23, 2017
    Anna Mathew, MD – “Role of Myeloperoxidase in Chronic Kidney Disease Accelerated Atherosclerosis"
  • May 16, 2017
    Jennifer Harder, MD – “Modeling Diabetic Kidney Disease with Kidney Organoids"
  • May 9, 2017
    Jennie Lin, MD, University of Pennsylvania – “From Genome to Novel Biology:  Functional Genomics in Cardiometabolic & Renal Diseases”
  • May 2, 2017
    Cristina Cebrian Ligero, MD – “Single cell transcriptional profiling of the developing human kidney"
  • April 18, 2017
    Edgar Otto, PhD – “Droplet-based single cell transcriptomic in Kidney Research”
  • April 11, 2017
    Ken Inoki, MD, PhD - "Regulation of Rheb Small GTPase in Cell Growth Control"
  • April 4, 2017
    Jeff Beamish, MD - "Engineered Extracellulr Matrices with Controlled Mechanics Modulate Renal Cell Proximal Tubular Cell Epithelialization"
  • March 28, 2017
    Matt Sampson, MD – “Empowering GWAS through a Nephrotic Syndrome Severity Score”
  • March 21, 2017
    Roger Wiggins, MD – “Podometrics as a Clinical Tool for Progression Management & Prevention"
  • March 14, 2017
    Vania Hinkovska-Galcheva, PhD - "Structural & Functional Analysis of 1-0 AcylceramideSynthase (Lysosomal Phospholipase A2): A Work in Progress"       
  • March 7, 2017 
    Raymond Yung, MD - "Obesity, Inflammation & Aging"   
  • February 28, 2017          
    Jeanie Park, MD - "Sypathetic Regulation During Physical Activity in Chronic Kidney Disease", Emory University
  • February 21, 2017        
    Yatrik Shah, PhD - "Hypoxia & Iron Metabolism: Fueling the Fire for Colon Cancer"
  • February 14, 2017          
    Alan Smrcka, PhD - "Regulation of Phospholipase C Epsilon (PLCE1) in the Heart"
  • January 31, 2017            
    Richard Miller, PhD - "Cool Stuff you can do with Slow-Aging Mice"
  • January 24, 2017
    James Shayman, MD - "New Insights into the structure and function of lysosomal phospholipase A2"
  • January 10, 2017            
    Sundararaman Swaminathan, MD - "Targeting Iron Homeostasis for Inducing Protection in Acute Kidney Injury"
  • December 13, 2016        
    Martin Myers, MD, PhD - “Molecular & Neural Mechanisms of Leptin Action”
  • December 6, 2016     
    Chip Brosius, MD - "Inflammation in Diabetic Kidney Disease: New Targets for Therapy"
  • November 29, 2016
    Kevin Atkins, PhD - "Altered Vascular Smooth Muscle GLUT4 Expression: Effect on Vascular Function in Diabetes and Beyond"
  • November 22, 2016
    Krishnan Raghavendran, MD - "Toll-like receptor 3 in lung injury"
  • November 8, 2016         
    Mats Ljungman, PhD - "Using nascent RNA Bru-seq to profile cellular responses to stress and re-programming"
  • November 2, 2016
    Steven Huang, MD - "Epigenetic Changes in Lung Fibroblasts: Insights into Novel Fibrogenic Pathways"
  • October 25, 2016
    Nick Lukacs, PhD - "Microbiome Alteration of Immune Responses and Targeting Pulmonary Disease"
  • October 18, 2016
    Eugene Chen, MD – “Advancing Lipid Gene Discoveries to Innovative Targets for Cardiovascular Disease”
  •  October 11, 2016            
    Lonnie Shea, PhD - "Regenerative Medicine: Preventing Tissue Degeneration & Promoting Regrowth"
  • October 4, 2016
    Shuichi Takayama, PhD - "Microfluidics & Organs on a Chip"
  • September 20, 2016      
    Bethany Moore, PhD - "Regulation of Pulmonary Fibrosis by Periostin"
  • September 13, 2016     
     Julie D. Saba, MD, PhD - "Mutations in Sgpl1 as a cause of focal segmentalglomerulosclerosis (FSGS)"
  • September 9, 2017
    Vincent Young, MD, PhD - "Microbial and Metabolic Aspects of C.difficile Infection in the Gut"

2015 - 2016

  • May 24, 2016
    Matthew Sampson, MD, MSCE - "The Genetic Determinants of Nephrotic Syndrome in Ann Arbor"
  • May 17, 2016
    Markus Bitzer, MD - "New Insights into 'Imploding' Glomerulopathy"
  • May 10, 2016
    Weibin Zhou, PhD - "Zebrafish Model of Nephrotic Syndrome"
  • May 3, 2016
    Roy Zent, M.D. - "Integrins in the Kidney"
  • April 12, 2016
    Greg Dressler, PhD. - "Developing Novel Small Molecules for Treating Renal Disease"
  • April 5, 2016
    Sanjeevkumar Patel, M.D. - "Pax2, Vasopressin Receptor and Lithium Nephrotoxicity: Is there a Link?"
  • March 29, 2016
    Evan A. Farkash, M.D., Ph.D. - "Make Antibody Mediated Rejection Diagnosis Great Again!"
  • March 22, 2016
    Joel M. Weinberg, M.D. - "New Insights Into Tubule Cell Injury and Death During Acute Kidney Injury"
  • March 15, 2016
    Maryam Afkarian, M.D., Ph.D. - "Using Omics to Understand Human Diabetic Kidney Disease"
  • December 8, 2015
    Jun Wu, Ph.D. - "Molecular Regulation and Therapeutic Potential of Brown and Beige Fat"
  • December 1, 2015
    Peter K. Henke, M.D. - "Experimental insights into post thrombotic syndrome"
  • November 24, 2015
    Jeffrey L. Platt, M.D. - "An Odd Tubular Cell: origin and implications"
  • November 10, 2015
    Stefan W. Stoll, Ph.D. - "The Membrane-Tethered Intracellular Domain of Amphiregulin Promotes Keratinocyte Proliferation"
  • October 27, 2015
    Paul Jenkins, Ph.D. - "Ankyrin and Spectrin: Critical Players in the Formation of Polarized Epithelia"
  • October 13, 2015
    Andrew J. Putnam, Ph.D. - "Microenvironmental Control of Cell Fate for Regenerative Applications"
  • October 6, 2015
    Roberto I. Vazquez-Padron, Ph.D., FAHA - "Understanding Arteriovenous Fistula Failure: What Have We Learned So Far?"
  • September 29, 2015
    Akira Ono, Ph.D. - "Driving HIV-1 Gag to the Virus Assembly Sites: Lipids and RNA are in Charge"
  • September 22, 2015
    Jason S. Knight, M.D., Ph.D. - "Neutrophils in the Antiphospholipid Syndrome: NET Gain in Understanding APS Pathogenesis?"

2014 - 2015

  • May 19, 2015
    - Subramaniam Pennathur, MBBS - "Tissue-Specific Metablolic Reprogramming Drives Enhanced Nutrient Flux in Diabetic Kidney Disease"
  • May 12, 2015
    - Zheng Dong, Ph.D. - "Mitochondrial Dynamics in Cell Death: A Tale of Two Membranes"
  • May 5, 2015
    - Cristina Cebrian, Ph.D. - "New in vivo and in vitro Models to Study Polycystic Kidney Disease"
  • April 21, 2015
    - Sangeevkumar R. Patel, M.D. - "An Update on the Roleof Pax2 and PTIP in Transcriptional Regulation"
  • April 14, 2015
    - Puneet Garg, M.D. - "Podocytes Have Low Levels of Basal Endocytic Flux"
  • March 31, 2015
    - Greg Dressler, Ph.D. - "Shifting the TGF-b/BMP Signaling Paradigm in Renal and Metabolic Disease"
  • March 24, 2015
    - Weibin Zhou, Ph.D. - "The Role of Caveolin-1 in Podocyte Injury"
  • March 17, 2015
    - Ken Inoki, M.D., Ph.D. - "Role of Ragulator in Podocytes
  • March 10, 2015
    - Tom Tuschl, Ph.D. - "RNA Regulation & RNA Diagnostics"
  • March 3, 2015
    - Edgar Otto, Ph.D. - "Pitfalls and Challenges in Autosomal Dominant Kidney Disease Gene Identification"
  • February 24, 2015
    - Randy J. Seeley, Ph.D. - "Bariatric Surgery: It's not what you think it is. Molecular mechanisms for the effects of surgery on obesity and diabetes"
  • February 17, 2015
    - Markus Bitzer, M.D. - "MicroRNA-Mediated Mechanism in Podoctye Injury"
  • February 10, 2015
    - Roger Wiggins, MB, BChir - "Progression as a Zero-Sum Game"
  • February 3, 2015
    - Bing Ye, Ph.D. - "The Regulation of the Golgi in Neuronal Polarity"
  • January 20, 2015
    - Jianping Fu, Ph.D. - "Hippo/YAP-Mediated Rigidity-Dependent Motor Neuron Differentiation of Human Pluripotent Stem Cells"
  • December 9, 2014
    - Ernestina Schipani, M.D., Ph.D. - "Hypoxia, HIFs and VHL in Development and Disease"
  • December 2, 2014
    - Henry Paulson, M.D., Ph.D. - "Ubiquitin Pathways in Neurodegenerative Disease"
  • November 25, 2014
    - Ormond A. MacDougald, Ph.D. - "Endocrine and Metabolic Functions of Marrow Adipose Tissue"
  • November 18, 2014
    - David B. Lombard, M.D., Ph.D. - "SIRT5 as a Novel Therapeutic Target in Cancer"
  • November 4, 2014
    - Arash Scott Soleimanpour M.D. - "Out with the old, in with the new...Mitophagy as a novel regulator of pancreatic beta cell function"
  • October 28, 2014
    - Gary D. Luker, M.D. - "Chemokine CXCL12: Multiple Isoforms and Effects"
  • October 14, 2014
    - Alisa Glukhova, M.D. - "Structure and Function of Lysosomal Phospholipase A2 and Lecithin: Cholesterol Acyltransferase"
  • October 7, 2014
    - Yatrik Shah, Ph.D. - "Intestinal Oxygen Dynamics in Systemic Iron Homeostasis"
  • September 30, 2014
    - Jordan Adam Shavit, M.D. - "Modeling Disorders of Hemostatis and Thrombosis Through Genome Editing in Zebrafish"
  • September 23, 2014
    - Cristen J. Willer, Ph.D. - "Understanding the Genetic Basis of Cardiovascular Disease and Related Risk Factors"
  • June 12, 2014
    - Andrey S. Shaw, M.D. - "THe Role of CD2AP in Podocyte Injury and Repair"