Chronic Kidney Disease and Related Long-Term Complications After Liver Transplantation.

Publication Type:

Journal Article


Adv Chronic Kidney Dis, Volume 22, Issue 5, p.404-11 (2015)


Disease Progression, End Stage Liver Disease, Female, Graft Rejection, Graft Survival, Humans, Kidney Failure, Chronic, Liver Transplantation, Male, Prognosis, Risk Assessment, Survival Analysis, Treatment Outcome


Liver transplantation is the standard of care for patients with decompensated cirrhosis. Liver transplantation recipients have excellent short-term and long-term outcomes including patient and graft survival. Since the adoption of model for end-stage liver disease (MELD)-based allocation policy, the incidence of post-transplant end stage renal disease has risen significantly. Occurrence of Stage 4 chronic kidney disease and end stage renal disease substantially increases the risk of post-transplant deaths. Because majority of late post-transplant mortality is due to nonhepatic post-transplant comorbidities, personalized care directed toward risk factor modification may further improve post-transplant survival.